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Gene Therapy in Tandem With Brain Cancer Research

By Rob Sutter


Tumors are, by nature, hard to treat which means that brain cancer research has to be done in a constant way. There is definitely an issue when it comes to the remedies that we have since they can have risks and side effects for certain patients. Nonetheless, those are what we have right now as we continually go about therapies in the hopes of finding new remedies. One new study may just be the ticket for new openings to come about in therapy construction.

An article posted on the Australian Broadcasting Corporation News website spoke about brain cancer research, more specifically how possible gene therapy methods can help it. The Children's Hospital in Westmead had made use of it, helping children who do not have alternative options to talk about. Chemotherapy is a commonly used treatment method but few know that it can destroy bone marrow if done in extreme doses. It can also increase the risk of infection, which organizations such as Voices Against Brain Cancer can cite.

This trial caught my interest and there are a number of reasons as to why this is. One of them involves the actual procedure, which starts from extracting bone narrow cells. The step to follow was the infusion of the gene taken from the DNA; this would work with the aforementioned cells so that bone marrow would become more resilient after chemo's side effects. The natural MGMT in one's body would also increase, allowing for a better degree of protection of bone marrow.

Before this kind of method can be utilized on a more constant basis, it's apparent that a number of phases have to be seen first. The first phase involves the safety and feasibility of the method; what good is a system going to be if it's going to negatively impact patients? This step cost $3.3 million but a good majority of it was funded thanks to charity. I can only hope that this process continues on so that maybe we will see more windows opening in terms of research.

I really hope that brain cancer research is done more on this matter for a number of reasons. While cures may come down the line, this is the kind of finding which can only open up the possibility for more therapies to be seen. This will, in turn, allow for easier access for potential remedies so that we may finally see an end to this condition. Between invasive surgery and chemotherapy, the findings that we have now may not work as well for some as they do for others.




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